Final answer:
The true statement about enzymes is that their activity is affected by temperature. Each enzyme typically has a single active site, demonstrating a high specificity for its substrate. Enzymes remain unchanged after the reaction and can catalyze additional reactions.
Step-by-step explanation:
The normal functioning of an enzyme involves a substrate binding specifically to the active site of the enzyme, forming an enzyme-substrate complex. This binding is determined by both the molecular shapes of the active site and the substrate. Enzymes are highly specific due to the shape of their active sites, following either a lock-and-key model or an induced fit model, meaning each enzyme typically catalyzes only one chemical reaction with a specific substrate.
Moreover, conditions such as temperature can greatly affect enzyme activity. After the catalytic reaction occurs, the products are released, and the enzyme remains unchanged, ready to catalyze subsequent reactions. Thus, the correct statement about the normal functioning of an enzyme is that temperature affects the activity of an enzyme.