Final answer:
The letter provides evidence of a hostile relationship between Powhatan and the Virginia colonists, characterized by violence and conflict.
Step-by-step explanation:
The letter is important because it provides evidence about the relationship between Powhatan and the Virginia colonists. The Powhatan were a large and powerful confederation of tribes in the region, and the English settlers had frequent conflicts with them.
The evidence from the letter suggests that the relationship between Powhatan and the Virginia colonists was one of hostility and violence. The Powhatan attacked the English settlers, killing hundreds of them, and the English responded by annihilating Powhatan villages.
This demonstrates the degree of resistance and conflict that resulted from English intrusion into the Powhatan confederacy.