Final answer:
The line of best fit can be used to make reliable predictions about the time it takes Charlie to complete a crossword puzzle. The slope of the line indicates a positive association between the variables. The correlation coefficient indicates a weak but significant association.
Step-by-step explanation:
The line of best fit can be used to make reliable predictions about the time it takes Charlie to complete a crossword puzzle. The equation y=0.376x + 15.48 represents the relationship between the number of clues, x, and the time required to complete the puzzle, y. The slope of the line of best fit is 0.376, which indicates a positive association between the variables. The correlation coefficient of 0.219 indicates a weak association, but it is still significant, meaning there is some relationship between the variables.