Final answer:
The two domains containing microscopic unicellular organisms are Domain Archaea and Domain Bacteria. These domains consist of prokaryotic cells without nuclei, differing in habitat and cell wall composition.
Step-by-step explanation:
The two domains that contain microscopic, unicellular organisms are Domain Archaea and Domain Bacteria. Both Domain Archaea and Domain Bacteria consist exclusively of unicellular prokaryotic organisms, which lack a nucleus. Despite their similarities, including asexual reproduction and the presence of cell walls, they differ significantly in their environmental habitats and the composition of their cell walls. Bacterial cell walls contain peptidoglycan, while Archaea typically thrive in extreme conditions and have different cell wall structures.
In contrast to these two domains, Domain Eukarya, which also includes some microscopic organisms like protists and certain fungi, is characterized by cells with a nucleus and other complex organelles. Though not wholly made up of unicellular organisms, this domain does encompass a major category of microscopic eukaryotic life. The distinct characteristics of each domain are essential for the classification and study of life on Earth, and understanding their differences helps in fields ranging from ecology to medicine.