Final answer:
The nurse should advise using a cold compress, over-the-counter pain medication if needed, and arm movement to alleviate pain at the injection site following an influenza vaccination, which is a common mild reaction.
Step-by-step explanation:
If a healthcare worker experiences pain at the site of an IM injection after receiving an annual influenza vaccination, it's generally considered a normal reaction. The nurse should recommend simple methods to alleviate the discomfort such as applying a cold compress to reduce swelling and pain, using an over-the-counter pain reliever if necessary, and moving the arm gently to help distribute the vaccine away from the muscle injection site. Most injection site reactions are mild and resolve on their own within a few days.