Final answer:
The answer aligned with the Anti-Federalist viewpoint is the need for a Bill of Rights to prevent government overreach.
Step-by-step explanation:
The statement that would align with the viewpoint of an Anti-Federalist is: "Without a Bill of Rights, the government might take advantage of citizens." Anti-Federalists were concerned that a strong national government might oppress citizens and infringe on individual rights without explicit protections. They advocated for a Bill of Rights to safeguard personal liberties and limit the federal government's power, in contrast to the Federalist belief in the need for a strong central government for a stable and effective nation.