Final answer:
Pancreatic enzyme replacement therapy is administered to CF patients who have malabsorption due to insufficient pancreatic enzyme production. The therapy provides essential enzymes for digestion, with dosages varying individually among patients.
Step-by-step explanation:
The true statement regarding pancreatic enzyme replacement therapy is that it is needed to treat cystic fibrosis (CF) patients with malabsorption. CF is a condition that affects the exocrine function of the pancreas, which can result in the insufficient release of pancreatic enzymes, such as trypsin, pancreatic amylase, and elastase. These enzymes assist in the digestion of proteins, carbohydrates, and fats, respectively. The therapy aims to supplement the missing enzymes, thus aiding in proper digestion and absorption of nutrients. The dosage is tailored to the individual's needs and can vary greatly among CF patients, depending on the extent of their exocrine pancreatic insufficiency and their diet.