Final answer:
The number of different combinations of even numbers on a 4-wheel combination lock with digits 1 to 5 is 250.
Step-by-step explanation:
The number of different combinations of an even number on a combination lock with 4 wheels, each having the digits 1 to 5 inclusive, can be determined using combinatorics.
Since the last digit must be even, there are 2 options: 2 or 4.
For the remaining 3 digits, there are 5 options for each digit. So the total number of combinations is 2 * 5 * 5 * 5 = 250.