Question

Avirulencefactorforabacterialdiseasecausingthetissuesloughingofnecrotizing fasciitis would be hyaluronidase.

a. True
b. False.

Answer 1

The statement is true. Hyaluronidase is an enzyme produced by some bacteria, and it is considered an avirulence factor. In the context of bacterial infections causing necrotizing fasciitis, hyaluronidase can contribute to the ability of bacteria to invade tissues by breaking down hyaluronic acid, a component of the extracellular matrix. This facilitates the spread of bacteria through tissues and contributes to the severity of the infection.

Answer 2

Hyaluronidase is a virulence factor, not an avirulence factor, for necrotizing fasciitis since it facilitates the spread of the infection, contradicting the statement in the question.

Step-by-step explanation:

The question pertains to the role of hyaluronidase as an avirulence factor for the bacterial disease necrotizing fasciitis. This is not accurate. Virulence factors are components that enable pathogens to overcome host defenses and establish infections. In the context of necrotizing fasciitis, which is a severe infection causing the death of tissues, virulence factors such as bacterial proteases contribute to the disease's severity by breaking down host tissues and evading immune response. Hyaluronidase acts as a spreading factor, enabling the infectious bacteria to invade further into the host tissues.

In summary, hyaluronidase would be considered a virulence factor, not an avirulence factor, as it aids in the progression of the disease by breaking down hyaluronic acid in connective tissues, thereby facilitating the spread of infection.