Question

A 24-hr urine collection had a total volume of 1,200 mL. 1:200 dilution was made and processed for creatinine, obtaining a result of 0.8mg/dl. What is the creatinine value in mg/dl in the urine sample? What is the result in terms of grams per 24 hours?

Answer 1

The creatinine concentration in the undiluted urine sample is 160 mg/dL, and the total creatinine excreted over 24 hours is 1.92 grams.

Step-by-step explanation:

To calculate the creatinine value in the urine sample that is undiluted, you multiply the diluted creatinine value by the dilution factor. Since the dilution was 1:200, the original concentration of creatinine is 0.8 mg/dL * 200 = 160 mg/dL. To find the total mass of creatinine excreted in 24 hours, you multiply the creatinine concentration (in mg/dL) by the total volume of the urine (in dL), which gives 160 mg/dL * 12 dL = 1920 mg/day. Converting this to grams, you have 1920 mg/day / 1000 = 1.92 g/day.

Therefore, the creatinine concentration in the urine sample is 160 mg/dL and the total amount excreted in 24 hours is 1.92 grams.