Final answer:
HPV is the virus that has E6 and E7 proteins which inactivate tumor suppressor genes like p53 and Rb. The E6 protein binds to p53 leading to its degradation, and E7 interferes with Rb, collectively contributing to the potential development of cervical cancer by disrupting cell cycle control.
Step-by-step explanation:
The Virus Known for E6 and E7 Proteins in Relation to Tumor Suppressor Genes: The virus known for having E6 and E7 proteins that inactivate tumor suppressor genes is the Human Papillomavirus (HPV). These two proteins play a critical role in the development of cancer, particularly cervical cancer. The E6 protein, in particular, binds to the tumor suppressor protein p53 and the consequence of this binding is the degradation of p53, a key protein that normally acts to prevent the development of tumors by repairing DNA or initiating cell death in case of severe DNA damage. The E7 protein also contributes to oncogenesis by interfering with another tumor suppressor protein, retinoblastoma protein (Rb).
Therefore, through these mechanisms, HPV can lead to uncontrolled cell growth and cancer.HPV's E6 and E7 proteins act as negative regulators of the host cell cycle by inactivating p53 and Rb, leading to the disruption of normal cell cycle control and enabling the potential for malignant transformation. These insights align with our understanding that oncogenic viruses can be either DNA or RNA viruses that are associated with various types of cancer caused by different viruses. Understanding how E6 and E7 disrupt cell regulation helps illuminate the ways HPV leads to cancer.