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Redraw Glycolysis and show the reactions of fructose metabolism (in both muscle and liver) and how they interact with glycolytic intermediates.

User Ed Manet
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Final answer:

Glycolysis is the metabolic pathway that breaks down glucose into pyruvate. Fructose metabolism involves the breakdown of fructose-6-phosphate to fructose-1,6-bisphosphate through the phosphorylation of fructose-6-phosphate by the enzyme phosphofructokinase.

Step-by-step explanation:

Glycolysis is the metabolic pathway that breaks down glucose into pyruvate. Fructose metabolism involves the breakdown of fructose-6-phosphate to fructose-1,6-bisphosphate through the phosphorylation of fructose-6-phosphate by the enzyme phosphofructokinase. In both muscle and liver, fructose metabolism interacts with glycolytic intermediates by participating in the same pathway. For example, fructose-1,6-bisphosphate goes through subsequent reactions in glycolysis to produce pyruvate. The process of glycolysis involves the breakdown of glucose into pyruvate, producing ATP and NADH in the process. Fructose metabolism in the liver and muscle interacts with glycolytic intermediates differently. In the muscle, fructose enters glycolysis after being phosphorylated to fructose-6-phosphate by hexokinase. In the liver, fructose is phosphorylated by fructokinase to fructose-1-phosphate, which is then split into glyceraldehyde and DHAP (dihydroxyacetone phosphate). Glyceraldehyde is subsequently phosphorylated to glyceraldehyde-3-phosphate, which can then enter the glycolysis pathway.

User Marco Kerwitz
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