Final answer:
An external stimulus can create an internal stimulus through both hormonal signaling and neural pathways.
Step-by-step explanation:
An external stimulus can create an internal stimulus through both hormonal signaling (A) and neural pathways (B), so the correct answer is C) Both A and B. Hormonal signaling involves the release of hormones in response to a stimulus, which then travel through the body and bind to receptors to stimulate a signaling pathway. Neural pathways, on the other hand, involve the activation of the nervous system in response to a stimulus, which can subsequently trigger the release of hormones. Both mechanisms play a role in transmitting and responding to external stimuli internally.