Question

ADH reduces output of urine by binding to ____ protein receptors called ______ receptors in the ________ membranes of the collecting tubule cells in the _______. The binding of ADH to its receptor activates _______ cyclase which converts ATP to the second messenger, __________. Protein Kinase A is activated by cAMP and triggers the movement of ________ containing vesicles to the ______ cell membrane. The aquaporins form channels in the cell membrane that allows the return of ______ from the kidney filtrate back into the ________.

Word Bank: G V2 luminal kidney blood cAMP water aquaporin adenylyl basolateral
A: V2, basolateral, luminal, kidney
B: G, aquaporin, kidney, blood
C: V2, luminal, basolateral, kidney
D: adenylyl, blood, luminal, kidney

Answer 1

ADH reduces urine output by binding to specific protein receptors in the kidney and activating a series of cellular processes that result in the reabsorption of water back into the blood.

Step-by-step explanation:

ADH reduces output of urine by binding to V2 protein receptors called basolateral receptors in the luminal membranes of the collecting tubule cells in the kidney. The binding of ADH to its receptor activates adenylyl cyclase which converts ATP to the second messenger, cAMP. Protein Kinase A is activated by cAMP and triggers the movement of water containing vesicles to the aquaporin cell membrane. The aquaporins form channels in the cell membrane that allows the return of water from the kidney filtrate back into the blood.