Final answer:
The Battles of Lexington & Concord were the events that first led to concerns over gun confiscation by the government, which influenced the creation of the Second Amendment.
Step-by-step explanation:
The event that first led the writers of the Second Amendment to worry that their guns might be taken by their government was the Battles of Lexington & Concord. These battles were the first military engagements of the American Revolutionary War, and they were sparked by British attempts to confiscate colonial weapons and ammunition. The experiences of the colonists during these conflicts underscored the importance of having the means to defend themselves against potential governmental overreach, directly influencing the drafting of the Second Amendment to ensure the right of the people to keep and bear arms.