Final answer:
The Pilgrims came to North America for religious reasons, wanting to separate from the Church of England. The English colonists at Jamestown and Roanoke came for economic reasons, seeking adventure and gold.
Step-by-step explanation:
The main reason for the Pilgrims coming to North America differed from that of the English colonists at Jamestown or Roanoke. The Pilgrims sought religious freedom, wanting to separate from the Church of England, which did not break away enough from Catholic Church practices. They had originally migrated to the Dutch Republic but felt they were losing their English identity and sailed to Plymouth to establish the Plymouth Colony. On the other hand, the English colonists at Jamestown and Roanoke came for economic reasons, seeking adventure and hoping to find gold.