Question

Which functional groups participate in peptide bond formation when amino acids are linked to form a protein? Select ALL that apply.

A. The amino group.
B. The hydrogen atom.
C. The carboxyl group.
D. The R group

Answer 1

Peptide bonds in proteins are formed between the amino group of one amino acid and the carboxyl group of another, through a dehydration synthesis reaction.

Step-by-step explanation:

The functional groups that participate in peptide bond formation when amino acids are linked to form a protein are the amino group (A) and the carboxyl group (C). During this reaction, a molecule of water is released. The peptide bond specifically links the carboxyl end of one amino acid with the amino end of another. This process is known as a dehydration synthesis reaction. Contrary to these active groups in peptide bonding, the hydrogen atom (B) and the R group (D), which is the amino acid side chain, do not directly partake in the formation of peptide bonds.