Question

Topical solutions for cleansing a clean and granulating wound should be noncytotoxic agents such as water and normal saline; these prevent the damage or the killing of the fibroblasts and the healing tissues. Acetic acid, hydrogen peroxide, and sodium hypochlorite are cytotoxic agents; these can be used for cleaning highly colonized wounds.

a. Acetic acid is suitable for granulating wounds
b. Hydrogen peroxide is noncytotoxic
c. Sodium hypochlorite prevents fibroblast damage
d. Normal saline is cytotoxic for granulating wounds

Answer 1

Correct wound care involves using noncytotoxic solutions like normal saline for clean and healing wounds to avoid damaging fibroblasts.

Step-by-step explanation:

When cleansing a clean and granulating wound, the goal is to aid healing while minimizing harm to the healing tissues. Solutions such as normal saline are preferred because they are noncytotoxic and do not damage the fibroblasts or the new granulation tissue.

It is incorrect to use hydrogen peroxide or acetic acid for granulating wounds as they are cytotoxic and potentially harmful to the healing process. Hydrogen peroxide can be cytotoxic, potentially leading to scarring or delayed healing, and should not be used on granulating wounds despite its continued use in some countries and for disinfecting items like contact lenses. Sodium hypochlorite can be used for highly colonized wounds but is also cytotoxic and not suitable for granulating wounds.

Therefore, options a, b, and c are incorrect because acetic acid is not suitable for granulating wounds, hydrogen peroxide is cytotoxic, and sodium hypochlorite does cause fibroblast damage. Option d is correct, as normal saline is noncytotoxic and is not harmful to granulating wounds.