Final answer:
Option A) and Option C). Severe or unusual headaches, visual disturbances, and unusual bleeding or discharge are significant adverse effects of combined oral contraceptives that should be promptly reported to a physician due to the risk of serious conditions.
Step-by-step explanation:
There are several negative effects of the combination oral contraceptives, some of which need to be reported right once to a physician. Unusual bleeding or discharge and vision problems are examples of adverse effects that need to be reported. These symptoms may be a sign of more serious adverse effects, such as an elevated risk of heart attack or stroke, blood clots, or malignancies like endometrial, breast, ovarian, or colon cancer. Furthermore, people should call their doctor right once if they have a headache that is strong, prolonged, or different from past headaches, or if they have any symptoms like a lump in the breast, trouble swallowing, changes to a mole or wart, or a persistent cough or hoarseness. These signs may indicate more serious illnesses that need to be treated right once.