Final answer:
The least restrictive replacement for a wrist restraint to prevent a resident from removing a feeding tube would be mittens, as they limit the ability to grasp the tube without being overly restrictive.
Step-by-step explanation:
The principle of least restriction is an important concept in healthcare, particularly when treating individuals who may be confused or have cognitive impairments. When a nurse is trying to prevent a confused resident from removing a feeding tube, the goal is to use the least restrictive method that is effective. Of the options provided, mittens would likely be the most appropriate replacement for a wrist restraint. Mittens can prevent the individual from grasping and pulling out the tube, yet they are less restrictive than wrist restraints, do not limit mobility to the extent a vest restraint would, and avoid the potential risks associated with administering a sedative. A tightly tucked sheet is generally not a restraint and would not effectively prevent the resident from accessing the tube.