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What studies are included in a grade A recommendation on the USC pyramid?

a) Meta-analyses or systematic reviews of randomized controlled trials

b) Randomized controlled trials

c) Cohort studies

d) Case-control studies

User Arsham
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Final answer:

A grade 'A' recommendation on the USPSTF evidence pyramid includes meta-analyses or systematic reviews of randomized controlled trials and randomized controlled trials. These are considered high-quality evidence due to their methodological rigor and systematic approach.

Step-by-step explanation:

The question relates to the level of evidence required for a grade 'A' recommendation on the United States Preventive Services Task Force (USPSTF) evidence pyramid. A grade 'A' recommendation is based on high-quality evidence, indicating that the USPSTF recommends the service and finds a high certainty that the net benefit is substantial. The studies included in a grade 'A' recommendation are:

  1. Meta-analyses or systematic reviews of randomized controlled trials
  2. Randomized controlled trials

These types of studies provide strong evidence due to the systematic approach and control over variables, which is indicated by the reference example given:

Speck, R. M., Courneya, K. S., Masse, L. C., Duval, S., & Schmitz, K. H. (2010). An update of controlled physical activity trials in cancer survivors: A systematic review and meta-analysis.

Journal of Cancer Survivorship

, 4, 87-100.

This example is a systematic review and meta-analysis of controlled trials, which fits the criteria for grade 'A' evidence, as it collates and synthesizes multiple randomized controlled trials relating to physical activity in cancer survivors.

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