Final answer:
The nurse should monitor serum potassium levels prior to administering hydrochlorothiazide (HCTZ) to ensure the client's potassium levels are within a safe range.
Step-by-step explanation:
Prior to administering hydrochlorothiazide (HCTZ), the nurse should monitor serum potassium levels. HCTZ is a diuretic that inhibits the Na/CI symporter in the distal convoluted tubule and collecting duct, resulting in the loss of Na+ and water. This can lead to hypokalemia, or low potassium levels, as potassium can be lost along with the sodium.
Therefore, monitoring serum potassium levels is important to ensure the client's potassium levels are within a safe range. If potassium levels are low, the nurse may need to administer potassium supplements or adjust the client's diet to include potassium-rich foods.