Final answer:
Ankle edema is a classic sign of kwashiorkor, a form of malnutrition due to protein deficiency, and should be identified as an indication of malnutrition in a patient who has experienced significant weight loss.
Step-by-step explanation:
The nurse should identify Ankle edema as an indication of malnutrition. When a client experiences significant weight loss, such as 5% within the past 30 days, it's crucial to assess for signs of malnutrition. Ankle edema is associated with kwashiorkor, a severe undernutrition syndrome caused by a lack of protein which can also present with a distended abdomen and is a classic sign of this type of protein-energy malnutrition. This is different from other potential symptoms such as moist skin, hyperreflexia, and dilated pupils, which are not direct indicators of malnutrition.