Final answer:
Ibuprofen and methotrexate are used to treat JRA by relieving pain and reducing inflammation in the joints. Ibuprofen is a nonsteroidal anti-inflammatory drug that inhibits the production of inflammatory chemicals, while methotrexate suppresses the immune system and reduces the activity of inflammatory cells.
Step-by-step explanation:
The medications ibuprofen and methotrexate are used to treat Juvenile Rheumatoid Arthritis (JRA) due to their ability to relieve pain and reduce inflammation in the joints.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of certain chemicals in the body that cause inflammation and pain. By reducing inflammation, ibuprofen helps alleviate the symptoms of JRA, such as joint pain and swelling.
Methotrexate is a disease-modifying antirheumatic drug (DMARD) that suppresses the immune system. In JRA, the immune system mistakenly attacks the body's own tissues, causing inflammation and joint damage. Methotrexate helps control the immune system and reduces the activity of inflammatory cells, thereby slowing down the progression of JRA and preventing joint damage.