Final answer:
Animals that are comatose are unresponsive to any stimuli, while nociceptive animals only respond to offensive stimulation such as pain.
Step-by-step explanation:
In biology, a comatose animal is unresponsive to any stimuli, while a nociceptive animal only responds to offensive stimulation such as pain. An example of a comatose animal would be a person in a deep coma who does not react to light, sound, or touch. An example of a nociceptive animal would be a rat that responds to the application of a painful stimulus like an electric shock.