Final answer:
The nurse should listen to the family's concerns, offer support to Mrs. Brandon, and facilitate an open conversation about her condition in a way that respects both her right to information and the family's wishes.
Step-by-step explanation:
The best response by the nurse in this scenario would be one that acknowledges Mrs. Brandon's need for information while also respecting the wishes of her family. The nurse should take a moment to speak with the family privately to understand their concerns about sharing the prognosis and to discuss the importance of honest communication with the patient. Afterwards, the nurse could return to Mrs. Brandon, offer a kind and supportive presence, and explain that a detailed discussion about her condition can be arranged with all parties involved to ensure that her questions and concerns are addressed with care and respect. It is crucial for the nurse to act as a liaison between the patient and her family, facilitating a conversation that respects the patient's right to know about her health while considering the family's perspective.