Final answer:
The lifetime risk of ovarian cancer for women with BRCA1 or BRCA2 mutation is approximately 40-45%. This risk is significantly higher than the general population.
Step-by-step explanation:
The lifetime risk of ovarian cancer for women with BRCA1 or BRCA2 mutation is approximately 40-45%. This means that about 40-45% of women with these mutations will develop ovarian cancer at some point in their lives. It's important to note that this risk is significantly higher than the general population, where the lifetime risk of ovarian cancer is about 1-2%.
For example, if 100 women with BRCA1 or BRCA2 mutations were followed over their lifetime, it is estimated that 40-45 of them would develop ovarian cancer.
Additionally, it is worth mentioning that the risk may vary between BRCA1 and BRCA2 mutations, with some studies suggesting a higher risk for BRCA1 mutations.