145k views
5 votes
what is the treatment of choice for hormonal therapy in the premenopausal woman with advanced breast cancer

User Nantoka
by
7.6k points

1 Answer

2 votes

Final answer:

Premenopausal women with advanced breast cancer often receive hormonal therapy through medications like tamoxifen or ovarian suppression drugs. These treatments block estrogen's effects or suppress ovarian function, which is crucial as estrogen can promote breast cancer growth. Treatment must be individualized and closely monitored due to varying risks and outcomes.

Step-by-step explanation:

The treatment of choice for hormonal therapy in a premenopausal woman with advanced breast cancer can vary based on specific clinical factors including the individual patient's hormone receptor status. However, a common approach might include the use of selective estrogen receptor modulators (SERMs), such as tamoxifen, or aromatase inhibitors alongside ovarian suppression. Tamoxifen is known to block the actions of estrogen in the breast tissue and is often used for hormone-receptor-positive breast cancer in premenopausal women. For those who require ovarian suppression, medications that suppress ovarian function, such as luteinizing hormone-releasing hormone (LHRH) agonists, can be used. There are ongoing debates and research about the long-term outcomes and risks of hormonal therapy, as studies have shown complex effects on cardio-vascular health and cancer risks.

It is critically important that individual treatment plans be discussed and implemented in conjunction with a healthcare provider specialized in oncology, considering the unique aspects of each case. Regular monitoring through pelvic and breast exams is also essential for those undergoing hormone treatment.

User Juan Bayona Beriso
by
8.4k points