140k views
2 votes
Phenylketonuria (PKU) is a disease that results from a recessive gene. Two normal parents produce a child with PKU.

1.What is the probability that a sperm from the father will contain the PKU allele?
2.What is the probability that an egg from the mother will contain the PKU allele?
3.What is the probability that their next child will have PKU?
4.What is the probability that their next child will be heterozygous for the PKU gene?

1 Answer

5 votes

Final answer:

1. The probability of the father's sperm containing the PKU allele is 50%. 2. The probability of the mother's egg containing the PKU allele is 50%. 3. The probability of their next child having PKU is 25%. 4. The probability of their next child being heterozygous for the PKU gene is 50%.

Step-by-step explanation:

1. The probability that a sperm from the father will contain the PKU allele is 1/2 or 50%. Since the father is normal and does not have PKU, he must be heterozygous for the PKU gene (carrier) with one normal allele and one PKU allele. Therefore, there is a 50% chance that a sperm will carry the PKU allele.

2. The probability that an egg from the mother will contain the PKU allele is also 1/2 or 50%. Just like the father, the mother must also be heterozygous for the PKU gene (carrier) with one normal allele and one PKU allele. Therefore, there is a 50% chance that an egg will carry the PKU allele.

3. The probability that their next child will have PKU is 1/4 or 25%. For the child to have PKU, both the sperm and the egg must carry the PKU allele. Since the probability of each parent's gamete carrying the PKU allele is 1/2, the probability of both gametes carrying the PKU allele is 1/2 * 1/2 = 1/4.

4. The probability that their next child will be heterozygous for the PKU gene is 1/2 or 50%. This is because there are two possible ways for the child to be heterozygous - either the sperm carries the PKU allele and the egg carries the normal allele, or vice versa. Each of these possibilities has a 1/2 probability, so the overall probability is 1/2 + 1/2 = 1/2.

User Adam Higgins
by
7.7k points