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Tra locus: Which protein is the first protein translated on the long polycistronic transcript (RNA) and recognizes oriT?

User Richardtz
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Final answer:

The first protein translated in bacterial conjugation at the Tra locus that recognizes oriT is part of an initiation complex, which is essential for beginning translation with the help of the 60S ribosomal subunit.

Step-by-step explanation:

The student's question pertains to the Tra (transfer) locus and which protein is the first to be translated on the long polycistronic transcript (RNA) which recognizes oriT. In bacterial conjugation, an initiation complex is responsible for beginning the process of translation. Upon scanning the mRNA, when an initiation complex finds open reading frame (ORF) start sites, it recruits the large 60S ribosomal subunit, linking 40S and 60S subunits to form a competent ribosome for translation. This initiation complex, often including an eIF2-2 protein complex, ensures that translation starts at the correct site. Specifically, proteins encoded by the tra locus are involved in the conjugative transfer of plasmids, which includes recognizing oriT, the origin of transfer, though the exact protein may vary depending on the context or specifics of the mechanism involved in a given organism.