Final answer:
The autoimmune disorder targeting Type V collagen fibers most likely affects the lungs, making C) lungs the correct answer to the question.
Step-by-step explanation:
Autoimmune diseases can affect various systems in the body, but the question specifically refers to an autoimmune disorder where an immune response targets Type V collagen fibers. Type V collagen is associated with the tissues of many organs, but when looking at diseases where Type V collagen is targeted, the lungs are most notably affected, as mentioned in the reference materials provided.
Therefore, among the options given, C) lungs would be the correct answer. This is confirmed when cross-referencing with the provided option stating that systemic lupus erythematosus can affect the heart, joints, lungs, skin, kidneys, central nervous system, and other tissues.