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Ehlers-Danlos syndrome and scurvy both are characterized by defects in

A) fibronectin.
B) desmosomes.
C) collagen.
D) dystrophin.
E) elastin.

User RedSIght
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1 Answer

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Final answer:

Ehlers-Danlos syndrome and scurvy are characterized by defects in collagen, which is essential for the structural integrity of different body tissues. While Ehlers-Danlos syndrome involves genetic defects in collagen production, scurvy is caused by a vitamin C deficiency impairing collagen formation.

Step-by-step explanation:

Ehlers-Danlos syndrome and scurvy are both characterized by defects in collagen. These conditions involve different underlying mechanisms affecting collagen, which is a critical protein for maintaining the structure and integrity of various tissues in the body. In Ehlers-Danlos syndrome, the defect arises from either a deficiency of the enzyme hydroxylase or mutations within the amino acid sequences involved in the synthesis of type-III collagen. This leads to progressive deterioration of collagen, particularly affecting joints, heart valves, organ walls, and arterial walls. Skin and vascular problems are commonly seen in those with Ehlers-Danlos syndrome, as the defective collagen impacts the structural stability of these areas.

On the other hand, scurvy results from a deficiency in vitamin C, which is a crucial cofactor for the proper deposition of collagen. The lack of vitamin C leads to weakened collagen, fragile capillaries, delayed wound healing, swollen gums, and poor dentition among other symptoms.

Given this information, the correct answer to the question is 'C) collagen.'

User Vaclav Elias
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