Question

Put the following steps of intramembranous ossification in the correct order.

1. Mesenchymal cells differentiate into osteoblasts. The osteoblasts then clump together and secrete matrix. This takes place in the ossification center.
2.Osteoblasts become encased in crystallized matrix. They then differentiate into osteocytes.
3.Over time, osteoblasts create a compact bone plate perforated with blood vessels along with a spongy bone center.
4.Blood vessels get trapped within the bone matrix.

Answer 1

The correct order of intramembranous ossification steps is: 1) forming ossification centers, 2) osteoblasts becoming osteocytes, 3) blood vessels becoming trapped within the matrix, and 4) development of compact bone and red marrow. This process is essential in forming flat bones.

Step-by-step explanation:

Correct Order of Intramembranous Ossification Steps

Intramembranous ossification is a crucial process in the formation of the flat bones of the skull, the mandible, and the clavicles. The correct sequential steps of intramembranous ossification are as follows:

Mesenchymal cells group into clusters, and ossification centers form.This process involves mesenchymal cells differentiating into osteoblasts, which secrete the extracellular matrix and trap blood vessels within the bone matrix. Over time, this material hardens and forms the spongy bone center and a plate of compact bone, while some connective tissue differentiates into red bone marrow.