Question

N-linked oligosaccharides on secreted glycoproteins are attached to ¬¬¬¬¬¬________.

(a) nitrogen atoms in the polypeptide backbone.
(b) the serine or threonine in the sequence Asn-X-Ser/Thr.
(c) the N-terminus of the protein.
(d) the asparagine in the sequence Asn-X-Ser/Thr.

Answer 1

N-linked oligosaccharides on secreted glycoproteins are attached to the asparagine residue within the Asn-X-Ser/Thr sequence, which is important for protein function and stability.

Step-by-step explanation:

N-linked oligosaccharides on secreted glycoproteins are attached to the asparagine in the sequence Asn-X-Ser/Thr. In the process of glycosylation in the rough endoplasmic reticulum, oligosaccharides begin by attaching a core glycan to asparagine via an N-glycosidic bond. These glycoproteins are then further processed in the Golgi apparatus where additional sugars may be added. N-linked glycosylation is an important post-translational modification that affects the folding, stability, and function of many proteins.