Final answer:
Neutralizing the positive charges on histone proteins would cause them to bind less tightly to the DNA, resulting in a more relaxed structure and easier access to the DNA for transcription.
Step-by-step explanation:
Neutralizing the positive charges on histone proteins would have the effect of reducing their attraction to the DNA. DNA is negatively charged, and the positive charges on the histone proteins enable them to bind tightly to the DNA. By neutralizing the positive charges, the histone proteins would bind less tightly to the DNA. This would result in a more relaxed structure and allow for easier access to the DNA for transcription.