Final answer:
The expedition led by Álvar Núñez Cabeza de Vaca off the coast of Florida encountered hostile Native American resistance. (option B)
Step-by-step explanation:
Cabeza de Vaca's expedition off the coast of Florida faced considerable challenges, with option B being correct. In 1528, while exploring the Gulf Coast, the expedition encountered hostility from Native American tribes, leading to a series of conflicts. Struggling with the harsh conditions, lack of resources, and clashes with indigenous populations, the expedition faced numerous hardships. Ultimately, survivors, including Cabeza de Vaca, were captured and enslaved by Native Americans, initiating a remarkable journey of survival and cultural adaptation that would later be chronicled in Cabeza de Vaca's narratives.
Cabeza de Vaca's expedition off the coast of Florida did not successfully establish a settlement or trade routes but faced challenges, particularly hostile Native American resistance. The expedition's encounters with indigenous peoples shaped the narrative of survival and adaptation, providing valuable insights into the complex interactions between European explorers and Native American communities during this early period of contact.