Final answer:
Syndication is a significant business in the television industry, generating substantial revenue and attracting national advertisers, proving its value beyond just less advertising clutter.
Step-by-step explanation:
The true statement about syndication among the options provided is that syndication has become a major business that generates revenue comparable to major networks. This defies the incorrect notions that syndicated programs are of limited value due to a smaller viewer base, that first-run syndication is the only form, that national advertisers rarely use syndicated programs, and that they are only attractive due to less advertising clutter. In fact, syndication offers the opportunity to reach diverse audiences and can indeed attract national advertisers, contributing significantly to the economic landscape of television broadcasting.