Final answer:
Comparative genomic hybridization can be used to detect chromosome structure changes such as deletions and duplications, but not typically translocations and inversions.
Step-by-step explanation:
Comparative genomic hybridization is a method that detects changes in chromosome structure, specifically identifying deletions and duplications. While cytogenetic mapping can show stained sections of chromosomes under a microscope, allowing for the analysis of the distance between genetic markers, it is not explicitly designed to identify translocations or inversions. Chromosomal translocations and inversions can be observed during meiosis, as homologous chromosomes must contort to pair effectively during prophase I due to structural rearrangements. Therefore, comparative genomic hybridization directly aids in the detection of deletions and duplications, but not necessarily translocations and inversions, which are more commonly identified during microscopic evaluation of meiotic cells.