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The recombinant % of two loci is 66%. Which one of the following is the explanation for this figure?

(A) The two loci are far apart and there is low linkage between them.
(B) The two loci are close together and there is high linkage between them.
(C) The recombinant fraction between the loci is low.
(D) The LOD score is high.

User Ravan
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Final answer:

The recombinant percentage of 66% indicates that the two loci are far apart with low linkage, as they are likely located very far apart on the same chromosome or on different chromosomes, leading to a high frequency of genetic recombination.

Step-by-step explanation:

The recombinant percentage (recombination frequency) is used to estimate the genetic distance between two loci on a chromosome. A recombinant % of 66% suggests that the two loci are not closely linked. They may either be located very far apart on the same chromosome, or they may be on different chromosomes. The correct answer is (A) The two loci are far apart and there is low linkage between them. When two genes are close together on the same chromosome, they tend to be transmitted through meiosis together, which would result in a low recombination percentage. Conversely, a high recombination percentage like 66% implies that these loci assort more independently, as if they were on separate chromosomes or very far apart on the same chromosome, suggesting that crossovers are more frequent during meiosis.

In genetics, recombination frequency correlates with genetic distance. This distance is expressed in centimorgans (cM), where 1% recombinant offspring equals 1 cM. A recombination frequency of 50% or higher typically indicates that genes are independently assortment or are far apart on the same chromosome, which corresponds with Mendel's law of independent assortment.

User Durumdara
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