Question

For each of the following sentences, fill in the blanks with the best word or phrase selected from the list below. Not all words or phrases will be used; each word or phrase should be used only once.

The human immune system produces __________________ of different immunoglobulins, also called __________________, which enable the immune system to recognize and fight germs by specifically binding one or a few related __________________. The hypervariable structural element that forms the ligand-binding site is comprised of several __________________. Purified antibodies are useful for a variety of experimental purposes, including protein purification using __________________ chromatography.

affinity billions ligands antibodies coiled-coils loops antigens hundreds size-exclusion β strands ion-exchange

Answer 1

The human immune system produces billions of different antibodies, which are immunoglobulins that target antigens. Variable loops and β strands form the ligand-binding sites, while affinity chromatography can be used for protein purification with antibodies.

Step-by-step explanation:

The human immune system produces billions of different immunoglobulins, also called antibodies, which enable the immune system to recognize and fight germs by specifically binding one or a few related antigens. The hypervariable structural element that forms the ligand-binding site is comprised of several loops and β strands. Purified antibodies are useful for a variety of experimental purposes, including protein purification using affinity chromatography.