Final answer:
Extracellular Chloride contributes to hydration, cation balance, and acid-base balance. Its concentration affects osmotic pressure and is regulated in the renal system.
Step-by-step explanation:
Extracellular Chloride plays an important role in maintaining proper hydration and balancing cations in the extracellular fluid (ECF). When extracellular chloride concentration is 65mM, it affects the osmotic pressure gradient between the intracellular fluid (ICF) and ECF. The movement of chloride ions relative to sodium ions in the renal system follows similar paths.
For example, when more sodium ions are reabsorbed, more chloride ions are secreted, and vice versa. Additionally, chloride is important in maintaining acid-base balance and aids digestion in the stomach.