Final answer:
Nociceptors are the first component in the pain transmission process, as they are the sensory receptors that detect harmful stimuli.
Step-by-step explanation:
The first component in the transmission of the pain stimulus is the stimulation of nociceptors. Nociceptors are specialized sensory receptors responsible for the sensation of potentially damaging stimuli, such as mechanical, chemical, or thermal stimuli that are typically painful. These receptors transduce and initiate the nociceptive signal that is then relayed through various pathways to the brain for perception as pain.