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Why does RNA polymerase make more mistakes than DNA polymerase?

A. RNA polymerase does not use a template molecule.

B. RNA polymerase does not have proofreading activity.

C. RNA polymerase uses completely different base-pairing rules.

D. RNA polymerase has a faulty mismatch repair system.

User LaborEtArs
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RNA polymerase does not have proofreading activity. Option B.

Why does RNA polymerase make more mistakes than DNA polymerase?

The main reason RNA polymerase makes more mistakes than DNA polymerase is that RNA polymerase lacks proofreading activity.

DNA polymerase, which is involved in DNA replication, has a proofreading mechanism that allows it to correct errors during synthesis. in the other hand, RNA polymerase, responsible for synthesizing RNA during transcription, it does not possess a similar proofreading function as DNA. This lack of proofreading makes RNA synthesis more error-prone compared to DNA replication.

User Maxim Zhukov
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