Final answer:
Single nucleotide changes from unrepaired DNA damage that lead to uncontrolled cell division can lead to cancer, resulting from the accumulation of mutations that disrupt cell cycle regulation and cause mutated cells to grow uncontrollably, forming tumors.
Step-by-step explanation:
Single nucleotide changes from unrepaired DNA damage that lead to uncontrolled cell division can lead to cancer. This condition occurs when the cell cycle is no longer regulated due to mutations in genes that regulate cell division. Such changes can result in a malfunctioning protein that is involved in the process of cell reproduction. While minor mistakes in DNA may initially occur, these can compound over time, leading to the accumulation of damage and eventually causing the cell cycle to speed up. As the effectiveness of control and repair mechanisms decreases, mutated cells outrun the growth of normal cells, potentially forming a tumor that is cancerous.