Question

Which of the following events directly triggers the initiation of replication at an ARS?

a. the departure of the ARS
b. the binding of other proteins to the ORC-origin complex
c. the departure of the ORC from the ARS
d. the binding of the ORC
e. the changing of the ARS into an ORC

Answer 1

The initiation of replication at an ARS is directly triggered by the binding of other proteins to the ORC-origin complex, marking the starting point for DNA replication.

Step-by-step explanation:

The event that directly triggers the initiation of replication at an Autonomously Replicating Sequence (ARS) is the binding of other proteins to the ORC-origin complex. In yeast, which is a eukaryote, ARS is an equivalent to the origin of replication in E. coli.

The Origin Recognition Complex (ORC) is a key component in the process of DNA replication. It binds to the ARS to mark the position where initiation will begin. Other necessary proteins then bind to the ORC-ARS complex, which stimulates the unwinding of DNA and the start of the replication process.