Final answer:
The limitations associated with the restoration of damaged nerve cells in the central nervous system include the inflammatory response, clearance of damaged tissue, and the distance for nerve regeneration. All these factors (A, B, and C) present significant challenges to the repair and proper functioning of injured neural tissues.
Step-by-step explanation:
One limitation associated with the restoration of damaged nerve cells within the central nervous system (CNS) is the inflammatory response. This response includes damaged tissue releasing chemical signals that lead to vasodilation and fluid leakage, causing redness, warmth, and swelling. If inflammation persists, it becomes chronic, which can hinder regeneration and lead to chronic pain.
Another limitation is the clearance of damaged tissue. The CNS contains microglia that engulf debris, but the process is not always efficient, and incomplete removal of damaged tissue can impede healing.
The distance that regenerating nerve fibers need to cover can also present a challenge, as nerve tissue in the CNS undergoes either slow regeneration or fails to repair at all.
Therefore, E. A, B, and C are all limitations of restoration when addressing damaged nerve cells within the central nervous system.