Final answer:
The lowered duplex stability of the DNA sequences flanking the ORC-binding site suggests that the nucleotide sequence in this area may have certain characteristics that contribute to reduced stability. For example, the presence of specific nucleotide motifs or structural features could lead to weaker base pairing interactions and decreased stability.
Step-by-step explanation:
The lowered duplex stability of the DNA sequences flanking the ORC-binding site suggests that the nucleotide sequence in this area may have certain characteristics that contribute to reduced stability. For example, the presence of specific nucleotide motifs or structural features could lead to weaker base pairing interactions and decreased stability. In this case, the flanking sequences may have a higher tendency for unpaired or mismatched bases, which can result in reduced stability of the DNA duplex.