Final answer:
The use of gunpowder weapons played a significant role in the establishment of large empires.
Step-by-step explanation:
The subject of this question is History. The question is discussing the factors that contributed to the expansion of empires and the establishment of large empires. The correct option that answers the question is D- States used gunpowder weapons to establish large empires. The use of gunpowder weapons, such as firearms and artillery, played a significant role in military advancements and allowed states to expand their territories and strengthen their armies.