Question

If G6P does not undergo glycolysis, what occurs?

a. It is converted into glycogen
b. It enters the citric acid cycle
c. It undergoes gluconeogenesis
d. It is converted into pyruvate

Answer 1

When G6P does not undergo glycolysis, it can be converted into glycogen for storage or used in gluconeogenesis to produce glucose.

Step-by-step explanation:

If glucose-6-phosphate (G6P) does not undergo glycolysis, which typically leads to the formation of pyruvate and the eventual entry into the citric acid cycle, it may alternatively be converted into glycogen or go through gluconeogenesis. When G6P is not directed towards glycolysis, it can serve as a precursor for the synthesis of glycogen, a storage form of glucose in the body, or it can be used to produce glucose through gluconeogenesis.

This implies that if G6P does not enter glycolysis, it does not produce pyruvate directly nor does it enter the citric acid cycle or undergo oxidative phosphorylation to produce ATP. Instead, it has alternative metabolic fates including the synthesis of glycogen or initiating the pathway for glucose synthesis in gluconeogenesis.