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What are free radical strand breaks and how are they formed?

User Reejesh PK
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Final answer:

Free radical strand breaks in DNA are caused by the interaction with free radicals, which can be initiated by ionizing radiation like UV light or cosmic rays. These breaks can lead to mutations or cell death if not properly repaired by the cell's DNA repair mechanisms.

Step-by-step explanation:

Free radical strand breaks refer to the breakage in DNA strands caused by the interaction with free radicals, which are highly reactive species containing one or more unpaired electrons. These breaks can occur due to exposure to certain types of ionizing radiation, such as from radioactive decay or cosmic rays.

The process of such break formation involves the absorption of energy by DNA molecules, leading to the cleavage of covalent bonds within the strands, creating free radicals.Free radicals can be initiated through various means, including exposure to UV light or other forms of radiation, which leads to the excitation of electrons and the breaking of weak bonds within molecules to form free radicals. These free radicals can then attack DNA, causing single and double-stranded breaks. The cell attempts to repair this damage through DNA repair mechanisms, but if the breaks are not correctly repaired, it can lead to mutations or cell death.

User ChAlexey
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